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Dried Leaf Extract Of Ginkgo Biloba Can Reduce The Damage Of Aluminum Salt To Cognitive Health

May. 14, 2019

Researchers at the Egyptian Atomic Energy Agency have found that Dried Leaf Extract Of Ginkgo Biloba has antioxidant properties that reduce the oxidative stress of aluminum chloride (AlCI3) on rat brain nerves. The results of this study have been published in the Journal of Nutrition.

It is well known that aluminum chloride is a powerful neurotoxin, and excessive intake can potentially cause a variety of neurodegenerative diseases, such as Alzheimer's disease. Previous studies have shown that the accumulation of aluminum in the brain is prone to cause ultrastructural changes, while aluminum chloride causes significant histopathological changes in the brain and testis. Given the effect of Ginkgo Biloba Extract Powder on brain health, the researchers suspected that it could reduce the toxins of aluminum chloride in the brain and testis of male mice.

In this study, the researchers divided 24 male mice into four groups, group 1 for the control group only for human distilled water, group 2 for 200 mg of ginkgo leaf extract; group 3 for 10 mg of aluminum chloride; group 4 first 200 mg of Ginkgo biloba extract and 10 mg of aluminum chloride. The study lasted for 3 months, after which the researchers examined the brain and pellets of the mice.

The results showed that the thiobarbituric acid-reactive substance (TBARS) in the brain and testis tissues of the aluminum chloride group was significantly increased, the cell damage was obvious, and the serum fluphenone was also significantly decreased. The content of TBARS in the brain and testis of Ginkgo biloba extract and aluminum chloride group was lower, and the contents of antioxidant superoxide dismutase (SOD), catalase (CAT) and glutathione (GSH) were observed.

Dried Leaf Extract Of Ginkgo Biloba


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